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KMID : 0356919930260020293
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Korean Journal of Anesthesiology
1993 Volume.26 No. 2 p.293 ~ p.298
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Cardiovascular Effect of Lidocaine in Patients under Halothane, Enflurane and Diazepam Anesthesia
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Abstract
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To evaluate the cardiovascular effect of lidocaine and serum electrolytes during inhalational or intravenous anesthesia, thirty-two healthy patients were randomly divided into three groups and measured systolic pressure, diastolic pressure, mean
pressure, heart rate and serum K+ and Na+ level were measured at 30 sec, 1, 3, 6,12 minutes after intravenous injection of lidocaine(1.5mg/kg) during halothane-N2O-O2 or enflurane-N2O-O2 or diazepam-N2O-O2 anesthesia.
In all 3 groups, the values of hemodynamic and serum electrolytes were not changed by 2% lidocaine.
These results indicate that intravenous injection of lidocaine(1.5mg/kg) to prevent undesirable reflexes and to prevent intracranial hypertension is a safe method without depression of hemodynamics.
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